Utility of Estrogen Receptor, Progesterone Receptor, and HER-2/neuAnalysis of Multiple Foci in Multifocal Ipsilateral Invasive Breast Carcinoma

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Utility of estrogen receptor, progesterone receptor, and HER-2/neu analysis of multiple foci in multifocal ipsilateral invasive breast carcinoma.

OBJECTIVES To determine the frequency of estrogen receptor (ER), progesterone receptor (PR), and HER-2/neu (HER2) testing multiple foci of ipsilateral invasive breast carcinoma at our institution and to evaluate resulting change in treatment recommendation. METHODS We identified 165 consecutive cases of multifocal invasive breast cancer over a 10-year period (2005-2014). Clinicopathologic fea...

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Background: Breast cancer is one of the most common women’s cancers, and the number of cases is increasing worldwide. Objective: The current study compared invasive lobular carcinoma (ILC) and invasive ductal carcinoma with regard to the prevalence of estrogen receptor (ER), progesterone receptor (PR), and age prevalence. Methods: T...

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PREDICTION OF ESTROGEN RECEPTOR STATUS OF INVASIVE DUCTAL CARCINOMA OF BREAST BY HISTOLOGIC GRADE

In human breast cancer, estrogen receptor (ER) status of the tumor has prognostic and therapeutic significance. However, facilities to study ER are not widely available to us. We postulated that if there is a correlation between histologic grade and ER status of invasive ductal carcinoma (IDC), it may help predict the ER status of the tumor. Of 8 4 cases of breast carcinoma referred to the ...

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Relation between Estrogen and Progesterone Receptor Status with p53, Ki67 and Her-2 Markers in Patients with Breast Cancer

Background: Breast cancer is the most common cancer in women, containing approximately one third of all illnesses in women. Assessment of molecular markers is valuable in predicting the outcome of disease and decision making for optimal treatment. The purpose of this study was to determine the relationship between estrogen and progesterone receptors with Her-2, Ki67, P53, and clinicopathologica...

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Evaluation Of The Androgen Receptor Status In Invasive Ductal Carcinoma Of Breast

  Background and Objective: Determination of hormone receptor status in the management of breast cancer is well-established. The aim of this study was to evaluate the frequency of androgen receptor (AR) expression in invasive ductal carcinoma of breast. Materials and Methods: For this purpose, 55 cases of invasive ductal breast carcinoma were examined using a monoclonal antibody against AR on...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2015

ISSN: 0002-9173,1943-7722

DOI: 10.1309/ajcpfwxp54olilmu